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Well before this, Australia had been well advanced in meeting the measures agreed upon under the Convention. Production, import and use of aldrin, chlordane , DDT, dieldrin, hexachlorobenzene (HCB), heptachlor , endrin, and toxaphene are not permitted in Australia. Production and importation of polychlorinated biphenyls (PCBs) are not permitted in Australia, with the phase-out of existing PCBs being managed under the National Strategy for the Management of Scheduled Waste. This strategy also addresses how Australia will manage HCB waste and organochlorine pesticides.

Valproic acid was first synthesized in 1882 by Beverly S. Burton as an analogue of valeric acid , found naturally in valerian . [66] Valproic acid is a carboxylic acid , a clear liquid at room temperature. For many decades, its only use was in laboratories as a "metabolically inert" solvent for organic compounds. In 1962, the French researcher Pierre Eymard serendipitously discovered the anticonvulsant properties of valproic acid while using it as a vehicle for a number of other compounds that were being screened for antiseizure activity. He found it prevented pentylenetetrazol -induced convulsions in laboratory rats . [67] It was approved as an antiepileptic drug in 1967 in France and has become the most widely prescribed antiepileptic drug worldwide. [68] Valproic acid has also been used for migraine prophylaxis and bipolar disorder. [69]

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