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SIDE EFFECTS:
It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.

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On the . black market one of the most popular preparations as of late is the new Boldenon 200 from Ttokkyo. This is the highest dosed version of this steroid ever produced, and is likewise in very high demand right now. This is of course a tremendous improvement over the 25 and 50mg products circulating exclusively just a couple of years ago. Before the Ttokkyo product Denkall had introduced us to the 100mg version of their Ultragan product, which remains a popular and trusted item on the black market today. Ganabol from Middle and South America is also common, and is typical sold in 50 ml vials. However this steroid is also produced in 10, 100, and 250 ml versions. Available in both 25 and 50 mg/ml version, one would look for a large “50” on the label indicating the stronger product. Equi-gan and Maxigan from Mexico are also common as of late, and are acceptable. A 50m1 vial of either usually sells for $250-300 on the black market. Unfortunately the weaker 25mg/ml products are usually very close in price.

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  • Citation tools Download this article to citation manager Furler John , O’Neal David , Speight Jane , Manski-Nankervis Jo-Anne , Gorelik Alexandra , Holmes-Truscott Elizabeth et al. Supporting insulin initiation in type 2 diabetes in primary care: results of the Stepping Up pragmatic cluster randomised controlled clinical trial BMJ 2017; 356 :j783
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    Equipoise results time

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  • Citation tools Download this article to citation manager Furler John , O’Neal David , Speight Jane , Manski-Nankervis Jo-Anne , Gorelik Alexandra , Holmes-Truscott Elizabeth et al. Supporting insulin initiation in type 2 diabetes in primary care: results of the Stepping Up pragmatic cluster randomised controlled clinical trial BMJ 2017; 356 :j783
    • BibTeX (win & mac) Download
    • EndNote (tagged) Download
    • EndNote 8 (xml) Download
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    • RIS (win only) Download
    • Medlars Download
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