I’m a drug addict who also suffers with psychosis, however, I know of many drug addicts with severe anxiety from my twelve step meetings. Most licenced anxiety meds are unsuitable/dangerous in the hands of addicts, this is compounded by what I have witnessed as the ineffective treatment with SSRIs and similar, if it wasn’t for antipsychotics many if these addicts would be so anxious that they would break under the weight of every craving. This new trend is helping to facilitate the sobriety and subsequent usefulness of some of societies most hopeless.
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Non-genetic, environmental, post-infectious, or psychosocial factors—while not causing Tourette's—can influence its severity.  Autoimmune processes may affect tic onset and exacerbation in some cases. In 1998, a team at the US National Institute of Mental Health proposed a hypothesis based on observation of 50 children that both obsessive–compulsive disorder (OCD) and tic disorders may arise in a subset of children as a result of a poststreptococcal autoimmune process.  Children who meet five diagnostic criteria are classified, according to the hypothesis, as having Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections ( PANDAS ).  This contentious hypothesis is the focus of clinical and laboratory research, but remains unproven.