“Attention-deficit drugs increase concentration in the short term, which is why they work so well for college students cramming for exams. But when given to children over long periods of time, they neither improve school achievement nor reduce behavior problems. The drugs can also have serious side effects... Many parents who take their children off the drugs find that behavior worsens, which most likely confirms their belief that the drugs work. But the behavior worsens because the children's bodies have become adapted [because the drugs are habit-forming] to the drug. Adults may have similar reactions if they suddenly cut back on coffee, or stop smoking.”
Chemotherapy can cause cardiac effects early in treatment, but in some cases, the effects may not show up until much later. One notable example is heart damage following treatment with the medication Adriamycin (doxorubicin ). With this drug, a possible long term side effect is weakening of the heart muscle, resulting in a decreased ability to pump blood through the body ( heart failure ). Symptoms may include increasing shortness of breath, fatigue, and swelling of the feet and ankles. If you have been treated with Adriamycin, your doctor may recommend a MUGA scan to monitor how your heart is pumping.
Benzodiazepine therapy can give rise to physiologic and psychologic dependence based on the drug's dosage, duration of therapy and potency. 1 Thus, dependence will develop sooner (such as in one to two months) in a patient who is taking a high dosage of a high-potency agent such as alprazolam than in a patient who is receiving a relatively low dosage of a long-acting, low-potency agent such as chlordiazepoxide. As a result of physiologic dependence, withdrawal symptoms emerge with rapid dose reduction or abrupt discontinuation of the drug.