If you’re a healthy guy in your 30s and 40s, your testosterone will be declining—but that doesn’t mean you actually need treatment. “If you go in and say, ‘Well, you know, in the past 10 years I’ve gotten more tired, I’m having trouble keeping weight off…’ that’s simply not enough—it’s a natural phenomenon!” Jacques Baillargeon, ., an epidemiologist at the University of Texas Medical Branch at Galveston, told Men’s Fitness. However, if you’re a man north of 50, and you’re having difficulty getting it up, you’re feeling depressed, and you’re generally unhappy, you should seek out TRT.
Transdermal patches (adhesive patches placed on the skin) may also be used to deliver a steady dose through the skin and into the bloodstream. Testosterone-containing creams and gels that are applied daily to the skin are also available, but absorption is inefficient (roughly 10%, varying between individuals) and these treatments tend to be more expensive. Individuals who are especially physically active and/or bathe often may not be good candidates, since the medication can be washed off and may take up to six hours to be fully absorbed. There is also the risk that an intimate partner or child may come in contact with the application site and inadvertently dose himself or herself; children and women are highly sensitive to testosterone and can suffer unintended masculinization and health effects, even from small doses. Injection is the most common method used by individuals administering AAS for non-medical purposes.