Clinical research still hasn’t determined a hard threshold level for when symptoms of low T begin appearing . Some recent research suggests that symptoms of low T might begin appearing in men when their total testosterone level dips below 320 ng/dl . According to anecdotal evidence from the owner of Peak Testosterone, many men start noticing low T symptoms when their total testosterone dips into the 400s . Of course, it’s anecdotal, so take it for what it’s worth, but it’s probably a good idea to stay above 500 ng/dl if you don’t want to experience symptoms of low T.
Dr. Samadi is a board-certified urologic oncologist trained in open and traditional and laparoscopic surgery and is an expert in robotic prostate surgery. He is chairman of urology, chief of robotic surgery at Lenox Hill Hospital and professor of urology at Hofstra North Shore-LIJ School of Medicine. He is a medical correspondent for the Fox News Channel's Medical A-Team and the chief medical correspondent for am970 in New York City. Learn more at . Visit Dr. Samadi's blog at . Follow Dr. Samadi on Twitter and Facebook.
Furthermore, pre-treatment total testosterone was an independent predictor of extraprostatic disease in patients with localized prostate cancer; as testosterone decreases, patients have an increased likelihood of non-organ confined disease and low serum testosterone levels are associated with positive surgical margins in radical retropubic prostatectomy. A clinical implication of these results concerns androgen supplementation which has become easier to administer with the advent of transdermal preparations (patch or gel) that achieve physiological testosterone serum levels without supra physiological escape levels. During the clinical development of a new testosterone patch in more than 200 primary or secondary hypogonadal patients, no prostate cancer was diagnosed.