Types of testosterone therapy

Neural injections of Bromodeoxyuridine (BrdU) were applied to males of both groups to test for neurogenesis . Analysis showed that testosterone and dihydrotestosterone regulated adult hippocampal neurogenesis (AHN). Adult hippocampal neurogenesis was regulated through the androgen receptor in the wild-type male rats, but not in the TMF male rats. To further test the role of activated androgen receptors on AHN, flutamide , an antiandrogen drug that competes with testosterone and dihydrotestosterone for androgen receptors , and dihydrotestosterone were administered to normal male rats. Dihydrotestosterone increased the number of BrdU cells, while flutamide inhibited these cells.

Note that the injection protocols and frequency for the purpose of TRT is never set in stone, and can always be adjusted according to the patient’s discussion and decision with their doctor. Often times many doctors will settle on an injection frequency with their patients of a once weekly injection for Testosterone Enanthate or Cypionate, for example. Many medical professionals have believed that the injection protocols as outlined by medical prescription guidelines require revision so as to ensure more frequent injection protocols in order to achieve more stable blood levels, but nevertheless, medical prescription guidelines remain as listed above. The general idea here, however, is to emphasize the fact that injection frequency can always be adjusted according to the individual’s needs, and especially following monitoring with blood work.

Now, how does this lead to shyness or a love of parties?  Well, imagine the extravert and the introvert both getting drunk, taking off their clothes, and dancing buck naked on a restaurant table. The next morning, the extravert will ask you what happened (and where are his clothes). When you tell him, he’ll laugh and start making arrangements to have another party. The introvert, on the other hand, will remember every mortifying moment of his humiliation, and may never come out of his room again. (I’m very introverted, and again I can vouch to a lot of this experientially! Perhaps some of you extraverts can tell me if he describes your experiences well, too -- assuming, of course, that you can remember you experiences!)

The partition coefficient of the ester in question is important because is effects how long the drug itself stays in the system. If the testosterone transfers too quickly from the oil to the blood, the result is a sudden spike in testosterone which then rapidly drops once the dose has been used up. In the example of free testosterone injected into the muscle from a water suspension (as in Aquiviron, mentioned above), the testosterone is essentially immediately available to the bloodstream due to its low partition coefficient, and thus there is an immediate spike of testosterone which is used up quickly in the body.

Types of testosterone therapy

types of testosterone therapy

The partition coefficient of the ester in question is important because is effects how long the drug itself stays in the system. If the testosterone transfers too quickly from the oil to the blood, the result is a sudden spike in testosterone which then rapidly drops once the dose has been used up. In the example of free testosterone injected into the muscle from a water suspension (as in Aquiviron, mentioned above), the testosterone is essentially immediately available to the bloodstream due to its low partition coefficient, and thus there is an immediate spike of testosterone which is used up quickly in the body.

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